Matrix SLA Update October 2023

SCREENING TESTS

TEST	CUT-OFF
pH (low range)	4
pH (high range)	9
Sample Dilution (Creatinine) (low range)	Between 5.6 mg/dL and 22.6 mg/dL
Sample Dilution (Creatinine) (high range)	Above 22.6 mg/dL
Specific Gravity (when Creatinine is <22.6 mg/dL) (low range)	1.001
Specific Gravity (when Creatinine is <22.6 mg/dL) (high range)	1.020
Sample Check (on request)	80 – 100%

URINE ETHYL ALCOHOL TESTING (UNPRESERVED URINE)
Results reported as value if above the cut-off or negative if below the cut-off
CUT-OFF	UNCERTAINTY OF MEASUREMENT (UoM%)
20 mg/dL	18
39 mg/dL (NWR Cut-Off)	18
40 mg/dL	17
67 mg/dL	15
107 mg/dL (Standard Cut-Off)	16

URINE DOA SCREENING TESTS (UNPRESERVED URINE)
PLEASE NOTE: HEALTHCARE AND WORKPLACE CUT-OFFS ARE THE SAME FOR URINE SCREENING ASSAYS
DRUG GROUP	METHOD OF ANALYSIS	CUT-OFF (ng/mL)	UNCERTAINTY OF MEASUREMENT (UoM%)
AMPHETAMINES (incl. METHAMPHETAMINES)	IMMUNOASSAY	300	10
BENZODIAZEPINES	IMMUNOASSAY	200	14
BARBITURATES	IMMUNOASSAY	200	4
BUPRENORPHINE	IMMUNOASSAY	5	14
CANNABIS	IMMUNOASSAY	50	6
COCAINE	IMMUNOASSAY	150	10
METHADONE (as EDDP)	IMMUNOASSAY	100	6
KETAMINE	IMMUNOASSAY	100	8
OPIATES	IMMUNOASSAY	300	8
6-MAM (Heroin Specific)	IMMUNOASSAY	10	8
PROPOXYPHENE	IMMUNOASSAY	300	8
PHENCYCLIDINE	IMMUNOASSAY	25	6
TRAMADOL	IMMUNOASSAY	200	14
LSD	IMMUNOASSAY	0.5	31
METHAQUALONE	IMMUNOASSAY	300	6

INTERCEPT 2 ORAL FLUID SCREENING TESTS† (†Values in table apply to concentrations in neat oral fluid)
PLEASE NOTE: HEALTHCARE AND WORKPLACE CUT-OFFS ARE THE SAME FOR ORAL FLUID SCREENING ASSAYS
DRUG GROUP	METHOD OF ANALYSIS	CUT-OFF (ng/mL)	UNCERTAINTY OF MEASUREMENT (UoM%)
AMPHETAMINES	IMMUNOASSAY	40	9
METHAMPHETAMINE	IMMUNOASSAY	40	21
BENZODIAZEPINES	IMMUNOASSAY	10	32
BUPRENORPHINE	IMMUNOASSAY	5	26
CANNABIS	IMMUNOASSAY	10	32
COCAINE	IMMUNOASSAY	30	20
METHADONE	IMMUNOASSAY	50	20
OPIATES	IMMUNOASSAY	40	12
6-MAM (Heroin Specific)	IMMUNOASSAY	4	27

CONFIRMATION TESTS

URINE CONFIRMATION TESTS (UNPRESERVED URINE)
DRUG/METABOLITE	HEALTHCARE CUT- OFF (ng/mL)	HEALTHCARE CUTOFF UoM%	WORKPLACE CUT- OFF (ng/mL)	WORKPLACE CUTOFF UoM%
AMPHETAMINES
AMPHETAMINE	100	23	200	18
METHAMPHETAMINE	100	17	200	15
MDA	100	17	200	15
MDEA	100	21	200	16
MDMA	100	22	200	17
BENZODIAZEPINES
DIAZEPAM	50	23	100	12
NORDIAZEPAM	50	20	100	12
OXAZEPAM	50	25	100	13
TEMAZEPAM	50	20	100	13
LORAZEPAM	100	16	100	16
BARBITURATES
AMOBARBITAL	120	27	150	24
BUTABARBITAL	120	26	150	25
PENTOBARBITAL	120	20	150	21
PHENOBARBITAL	120	17	150	16
SECOBARBITAL	120	25	150	25
BUPRENORPHINE
BUPRENORPHINE*	2	8	2	8
NORBUPRENORPHINE*	2	39	2	39
CANNABINOIDS
THC-COOH (CANNABIS METABOLITE)	15	32	15	32
COCAINICS
AEME (CRACK COCAINE MARKER)	75	12	75	15
BENZOYLECGONINE	75	24	75	26
COCAINE	75	16	75	19
METHADONE
EDDP (METHADONE METABOLITE)	37.5	16	75	17
METHADONE	75	25	250	16
KETAMINE
KETAMINE	15	15	75	15

URINE CONFIRMATION TESTS (UNPRESERVED URINE) contd.
DRUG/METABOLITE	HEALTHCARE CUT- OFF (ng/mL)	HEALTHCARE CUTOFF UoM%	WORKPLACE CUT- OFF (ng/mL)	WORKPLACE CUTOFF UoM%
CATHINONES
CATHINONE	100	19	200	18
MDPV	100	24	200	18
METHCATHINONE	100	24	200	20
MEPHEDRONE	100	27	200	20
OPIATES
CODEINE	150	19	300	18
DIHYDROCODEINE	150	18	300	14
MORPHINE	150	20	300	18
6-MONOACETYLMORPHINE (6-MAM)	10	37	10	37
PROPOXYPHENE	240	17	300	19
PHENCYCLIDINE
PHENCYCLIDINE	20	12	25	13
LSD
2-OXO-3-HYDROXY-LSD (LSD METABOLITE)	1	43	1	34
METHAQUALONE
METHAQUALONE	240	12	300	14
TRAMADOL
TRAMADOL	100	20	250	18
GABAPENTINOIDS
PREGABALIN	100	24	100	24
GABAPENTIN	50	23	100	19
OTHER
OXYCODONE	100	22	N/A	N/A
THEBAINE	5	40	5	41
*Analysis will be outsourced to a ISO17025 approved laboratory

INTERCEPT 2 ORAL FLUID CONFIRMATION TESTS† (†Values in table apply to concentrations in neat oral fluid)
DRUG/METABOLITE	HEALTHCARE CUT- OFF (ng/mL)	HEALTHCARE CUTOFF UoM%	WORKPLACE CUT- OFF (ng/mL)	WORKPLACE CUTOFF UoM%
AMPHETAMINES
AMPHETAMINE	6	16	15	12
METHAMPHETAMINE	6	13	15	12
MDA	6	23	15	20
MDEA	6	18	15	14
MDMA	6	17	15	13
BENZODIAZEPINES
DIAZEPAM	2	17	3	13
NORDIAZEPAM	2	25	3	21
OXAZEPAM	3	32	3	32
TEMAZEPAM	2	18	3	16
LORAZEPAM	3	29	3	29
BUPRENORPHINE
BUPRENORPHINE	1	32	1	34
CANNABINOIDS
THC	2	24	2	14
COCAINICS
AEME (CRACK COCAINE MARKER)	8	36	8	36
BENZOYLECGONINE	8	18	8	18
COCAINE	1.6	26	8	17
METHADONE
EDDP (METHADONE METABOLITE)	4	23	20	15
METHADONE	4	12	20	10
KETAMINE
KETAMINE	1.6	25	8	13
CATHINONES
CATHINONE	6	25	30	26
MDPV	6	22	30	12
METHCATHINONE	6	34	30	34
MEPHEDRONE	6	13	30	11
OPIATES
CODEINE	8	28	15	21
DIHYDROCODEINE	8	22	15	18
MORPHINE	8	26	15	19
6-MONOACETYLMORPHINE (6-MAM)**	2	66	2	60

INTERCEPT 2 ORAL FLUID CONFIRMATION TESTS† (†Values in table apply to concentrations in neat oral fluid)
DRUG/METABOLITE	HEALTHCARE CUT- OFF (ng/mL)	HEALTHCARE CUTOFF UoM%	WORKPLACE CUT- OFF (ng/mL)	WORKPLACE CUTOFF UoM%
TRAMADOL
TRAMADOL	4	15	20	10
GABAPENTINOIDS
PREGABALIN	4	18	20	15
GABAPENTIN	4	16	20	12
**        Testing validated but not accredited